An **Anti-DNase B (Anti-Deoxyribonuclease B) Serum test** measures antibodies produced by the body in response to a group A *Streptococcus* bacterial infection. While a sore throat is the most common presentation, this specific test is exceptionally valuable for detecting recent **streptococcal skin infections (impetigo)**, where other tests like ASOT can sometimes fail.

Evaluating Anti-DNase B levels helps doctors confirm past strep exposure when investigating delayed, serious complications. These include **acute post-streptococcal glomerulonephritis** (a kidney inflammatory disorder) and **rheumatic fever**, ensuring patients receive the correct, targeted long-term care.