Anti Mitochondrial Antibody test New
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The **Anti-Mitochondrial Antibody (AMA) test** is a specialized blood test used primarily to diagnose Primary Biliary Cholangitis (PBC), a chronic and progressive autoimmune liver disease. Mitochondria serve as the energy powerhouses within cells, but in patients with PBC, the immune system mistakenly produces autoantibodies that target these structures. This autoimmune attack causes inflammation and scarring of the small bile ducts inside the liver, potentially leading to liver failure if left untreated.

A positive AMA test—particularly the highly specific AMA-M2 subtype—is detected in approximately 90% to 95% of individuals with PBC, making it a definitive diagnostic marker.
The **Anti-Mitochondrial Antibody (AMA) test** is a specialized blood test used primarily to diagnose Primary Biliary Cholangitis (PBC), a chronic and progressive autoimmune liver disease. Mitochondria serve as the energy powerhouses within cells, but in patients with PBC, the immune system mistakenly produces autoantibodies that target these structures. This autoimmune attack causes inflammation and scarring of the small bile ducts inside the liver, potentially leading to liver failure if left untreated. A positive AMA test—particularly the highly specific AMA-M2 subtype—is detected in approximately 90% to 95% of individuals with PBC, making it a definitive diagnostic marker.
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