A CD23 test is a specialized laboratory assay used to evaluate the expression of the CD23 protein, a low-affinity IgE receptor predominantly found on mature B cells, activated macrophages, and eosinophils. Commonly performed via flow cytometry or immunohistochemistry on blood or tissue samples, this test plays an important role in diagnosing and monitoring B-cell lymphoproliferative disorders, notably Chronic Lymphocytic Leukemia (CLL) where CD23 is characteristically expressed.
Additionally, measuring soluble CD23 levels can aid in assessing allergic disease severity and inflammatory conditions, providing valuable diagnostic and prognostic insight for targeted patient management.